Rhythm Pharmaceuticals, Inc. (RYTM)

NASDAQ: RYTM · Real-Time Price · USD
94.17
-2.06 (-2.14%)
At close: May 8, 2026, 4:00 PM EDT
92.34
-1.83 (-1.94%)
After-hours: May 8, 2026, 6:41 PM EDT
Market Cap6.45B +62.1%
Revenue (ttm)217.17M +58.7%
Net Income-207.84M
EPS-3.14
Shares Out 68.53M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume882,543
Open95.79
Previous Close96.23
Day's Range93.24 - 96.76
52-Week Range55.31 - 122.20
Beta1.94
AnalystsStrong Buy
Price Target131.93 (+40.1%)
Earnings DateMay 5, 2026

About RYTM

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company’s lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Oct 5, 2017
Employees 414
Stock Exchange NASDAQ
Ticker Symbol RYTM
Full Company Profile

Financial Performance

In 2025, Rhythm Pharmaceuticals's revenue was $189.76 million, an increase of 45.83% compared to the previous year's $130.13 million. Losses were -$201.92 million, -23.68% less than in 2024.

Financial Statements

Analyst Summary

According to 14 analysts, the average rating for RYTM stock is "Strong Buy." The 12-month stock price target is $131.93, which is an increase of 40.10% from the latest price.

Price Target
$131.93
(40.10% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Rhythm Pharmaceuticals price target raised to $143 from $140 at Canaccord

Canaccord raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $143 from $140 and keeps a Buy rating on the shares. The firm said the company delivered a topline

2 days ago - TheFly

Rhythm Pharmaceuticals Announces Participation in Upcoming Bank of America Global Healthcare Conference

BOSTON, May 06, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

4 days ago - GlobeNewsWire

Rhythm Pharmaceuticals Earnings Call Transcript: Q1 2026

Q1 2026 saw $60.1M in revenue, driven by BBS and a strong U.S. launch of IMCIVREE for acquired HO, with over 150 start forms and positive payer response. International expansion advanced with EU approval and Japan NDA filing, supporting a robust outlook for 2026.

5 days ago - Transcripts

Rhythm Pharmaceuticals reports Q1 EPS (83c), consensus (86c)

Reports Q1 revenue $60.11M, consensus $56.07M. “The U.S and European approvals of IMCIVREE mark a transformational milestone for patients with acquired hypothalamic obesity who, until now, had no appr...

5 days ago - TheFly

Rhythm Pharmaceuticals sees FY26 operating expenses $385M-$415M

Meeker added, “In addition, we continue to advance our MC4R agonism pipeline with upcoming data readouts from ongoing trials of setmelanotide in Prader-Willi syndrome and our weekly injectable, RM-718...

5 days ago - TheFly

Rhythm Pharmaceuticals Reports First Quarter 2026 Financial Results and Business Update

-- IMCIVREE ® (setmelanotide) launched in the U.S. for acquired hypothalamic obesity; more than 150 patient start forms received in the first six weeks following FDA approval on March 19, 2026 -- -- F...

5 days ago - GlobeNewsWire

Rhythm Pharmaceuticals presents Phase 3 TRANSCEND trial data

Rhythm Pharmaceuticals (RYTM) announced the presentation of new data delivered by Rhythm and its partners at The Pediatric Endocrine Society Annual Meeting. “The data presented provide important longe...

6 days ago - TheFly

Rhythm Pharmaceuticals Announces New Data Presentations in Acquired Hypothalamic Obesity at Pediatric Endocrine Society

-- Pediatric patients (n=10) with acquired hypothalamic obesity achieved sustained reductions in BMI and BMI-Z at 2.5 years of setmelanotide therapy -- -- Weight category improvements observed in pedi...

6 days ago - GlobeNewsWire

Rhythm Pharmaceuticals’ Imcivree granted MAA in Europe for obesity

Rhythm Pharmaceuticals (RYTM) announced the European Commission, or EC, has expanded the marketing authorization for Imcivree – setmelanotide – to include the treatment of obesity and control of hunge...

9 days ago - TheFly

Rhythm Pharmaceuticals Announces IMCIVREE® (Setmelanotide) Granted Marketing Authorization by European Commission for the Treatment of Obesity and Control of Hunger in Patients with Acquired Hypothalamic Obesity

-- First therapy to be FDA-approved and EC-authorized for acquired hypothalamic obesity -- -- European Commission grants authorization in adults and children 4 years of age and above with acquired hyp...

9 days ago - GlobeNewsWire

Rhythm Pharmaceuticals Transcript: 25th Annual Needham Virtual Healthcare Conference

IMCIVREE’s U.S. launch for acquired HO is underway, with expansion planned in Europe and Japan. Key pipeline updates include mid-year PWS data and phase III studies for new agents. The company is focused on rare MC4R pathway diseases, with strong cash reserves and a long-term vision for global leadership.

23 days ago - Transcripts

Rhythm Pharmaceuticals to Report First Quarter 2026 Financial Results on Tuesday, May 5, 2026

BOSTON, April 09, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with ra...

4 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals price target raised to $136 from $130 at RBC Capital

RBC Capital raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $136 from $130 and keeps an Outperform rating on the shares as part of the firm’s broader research

4 weeks ago - TheFly

Rhythm Pharmaceuticals appoints Popovits to board of directors

Rhythm Pharmaceuticals (RYTM) announced changes to its Board of Directors, including the appointment of Kim Popovits and the departure of Ed Mathers. Popovits previously served as Chairman of the Boar...

4 weeks ago - TheFly

Rhythm Pharmaceuticals Announces Changes to Board of Directors

-- Kim Popovits appointed as new Director; Ed Mathers to depart -- BOSTON, April 03, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical c...

5 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals Receives Positive CHMP Opinion for IMCIVREE® (setmelanotide) for the Treatment of Obesity and Control of Hunger in Patients with Acquired Hypothalamic Obesity due to Hypothalamic Injury or Impairment

-- European Commission decision anticipated in second quarter of 2026 -- BOSTON, March 26, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceut...

6 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals price target raised to $105 from $100 at H.C. Wainwright

H.C. Wainwright analyst Raghuram Selvaraju raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $105 from $100 and keeps a Buy rating on the shares after the FDA approved

6 weeks ago - TheFly

Rhythm Pharmaceuticals selects Pantherx Rare as pharmacy for Imcivree

PANTHERx Rare Pharmacy announced that it was selected by Rhythm Pharmaceuticals (RYTM) as the exclusive U.S. Pharmacy distribution partner for the expanded indication of IMCIVREE for adults and childr...

7 weeks ago - TheFly

PANTHERx® Rare Selected by Rhythm Pharmaceuticals Inc. as the Exclusive U.S. Specialty Pharmacy for the Expanded Indication for IMCIVREE® (setmelanotide)

PITTSBURGH, March 20, 2026 /PRNewswire/ -- PANTHERx® Rare Pharmacy, the trusted leader and innovator in patient access and support services for personalized rare disease care, announced that it was se...

7 weeks ago - PRNewsWire

Rhythm Pharmaceuticals price target raised to $149 from $139 at BofA

BofA analyst Tazeen Ahmad raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $149 from $139 and keeps a Buy rating on the shares after the company announced FDA

7 weeks ago - TheFly

Rhythm Pharmaceuticals price target raised to $142 from $131 at Citi

Citi analyst Samantha Semenkow raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $142 from $131 and keeps a Buy rating on the shares after the FDA approved Imcivree

7 weeks ago - TheFly

Rhythm Pharmaceuticals price target raised to $155 from $152 at Citizens

Citizens raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $155 from $152 and keeps an Outperform rating on the shares. FDA approval for hypothalamic obesity substantially expands Imc...

7 weeks ago - TheFly

Rhythm Pharmaceuticals trading resumes

19:05 EDT Rhythm Pharmaceuticals (RYTM) trading resumes

7 weeks ago - TheFly

Rhythm Pharmaceuticals Transcript: Study update

IMCIVREE received FDA approval for acquired hypothalamic obesity, supported by phase III data showing significant BMI and hunger reductions. The launch targets a US population of about 10,000, with expanded sales and patient support teams, and ongoing efforts to secure broad payer coverage and international approvals.

7 weeks ago - Transcripts

Rhythm Pharmaceuticals trading halted, news pending

18:25 EDT Rhythm Pharmaceuticals (RYTM) trading halted, news pending

7 weeks ago - TheFly